Formating result: Z24WWEVE012
Gene: Mycoplasma pneumoniae adhesin protein (P30) gene
Organism: Mycoplasma pneumoniae
Accesion number: EF614306.1
PubMed: 18032594
Max score: 1524
Totral score: 2739
Query coverage: 100%
E value: 0.0
Max ident: 100%
LOCUS EF614306 825 bp DNA linear BCT 18-MAR-2008
DEFINITION Mycoplasma pneumoniae adhesin protein (P30) gene, complete cds.
ACCESSION EF614306
VERSION EF614306.1 GI:148729625
KEYWORDS .
SOURCE Mycoplasma pneumoniae
ORGANISM Mycoplasma pneumoniae
Bacteria; Firmicutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
REFERENCE 1 (bases 1 to 825)
AUTHORS Varshney,A.K., Chaudhry,R., Kabra,S.K. and Malhotra,P.
TITLE Cloning, expression, and immunological characterization of the P30
protein of Mycoplasma pneumoniae
JOURNAL Clin. Vaccine Immunol. 15 (2), 215-220 (2008)
PUBMED 18032594
REFERENCE 2 (bases 1 to 825)
AUTHORS Varshney,A.K., Chaudhry,R., Malhotra,P. and Kabra,S.K.
TITLE Direct Submission
JOURNAL Submitted (17-MAY-2007) Microbiology, All India Institute of
Medical Sciences, Ansari Nagar, New Delhi 110029, India
source 1..825
/organism="Mycoplasma pneumoniae"
/mol_type="genomic DNA"
/isolation_source="clinical sample"
/db_xref="taxon:2104"
gene 1..825
/gene="P30"
CDS 1..825
/gene="P30"
/codon_start=1
/transl_table=4
/product="adhesin protein"
/protein_id="ABR09215.1"
/db_xref="GI:148729626"
/translation="MKLPPRRKLKLFLLAWMLVLFSALIVLATLILVQHNNTELTEVK
SELSPLNVVLHAEEDTVQIQGKPITEQAWFIPTVAGCFGFSALAIILGLAIGLPIVKR
KEKRLSEEKERQEQLAEQLQRISAQQEEQQALEQQAAAEAHAEAEVEPAPQPVPVPPQ
PQVQINFGPRTGFPPQPGMAPRPGMPPHPGMAPRSGFPPQPGMAPRPGMPPHPGMAPR
PGFPPQPGMAPRPGMPPHPGMAPRPGFPPQPGMAPRPGMQPPRPGMPPQPGFPPKR"
ORIGIN
1 atgaagttac cacctcgaag aaagcttaaa ctgtttttat tagcctgaat gctagtgctg
61 ttcagcgctt taatagtgct tgcaacctta attttggtac agcacaacaa taccgaactg
121 acagaagtta agagtgaatt gagtcccctt aacgttgttt tacacgcaga agaggataca
181 gtacaaattc agggcaagcc gattactgag caagcatggt ttattcctac agttgctggt
241 tgctttggtt ttagtgccct agccatcatc ttgggccttg ctataggact gccaattgtg
301 aagcgcaagg aaaaacgctt atcggaggaa aaggaacgcc aagaacagtt agcggaacag
361 ctacaacgca tttctgccca acaagaagag caacaagcgt tagaacaaca agcagctgct
421 gaagcccatg ctgaagcgga agttgaacca gcaccacaac cagtaccagt accacctcaa
481 ccccaagtcc aaattaactt cggtccccgt actggtttcc cacctcaacc cggtatggcg
541 cctcgtccag gtatgccgcc acaccccggt atggctccaa gatctggttt cccacctcaa
601 cccggtatgg cgcctcgtcc aggtatgccg ccacaccccg gtatggctcc aagacctggt
661 ttcccacctc aacccggtat ggcgcctcgt ccaggtatgc cgccacaccc cggtatggct
721 ccaagacctg gtttcccacc tcaacccggt atggcgcctc gtcccggaat gcaaccacca
781 cgtcctggca tgccacccca acccggtttt ccaccaaaac gctaa
2 comments:
Can some one explain the function of this gene that you had identify?
This gene (adhesin protein P30) associated with cell development of M.pneumonia. P30 mutants (II-3 and II-7) support adhesin P1's receptor-binding function by localizing P1 to the attachment organelles.The loss of mutants P30 accompanied by the inability to cytadhere, the failure to localize adhesin P1 to the attachment organelle, an altered morphology, and avirulence.
Post a Comment